Rise in AGIO’s short interest indicates Bearish sentiment

Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Agios Pharmaceuticals Inc shares valued at $452,632 were purchased by SARAH GHEUENS on Jul 09 ’25. At $37.99 per share, SARAH GHEUENS acquired 11,914 shares.

Also, Gheuens Sarah sold 4,091 shares, netting a total of over 139,789 in proceeds. Following the sale of shares at $34.17 each, the insider now holds 61,271 shares.

Before that, Gheuens Sarah had added 4,091 shares to its account. In a trade valued at $140,608, the Officer bought Agios Pharmaceuticals Inc shares for $34.37 each.

As published in their initiating research note from H.C. Wainwright on February 24, 2025, Agios Pharmaceuticals Inc [AGIO] has been a Buy and the price target has been revised to $58. Analysts at Scotiabank started covering the stock with ‘”a Sector outperform”‘ outlook in a report released in mid October. Earlier on September 27, 2024, Leerink Partners downgraded its rating. Their new recommendation was “a Market perform” for AGIO stock which previously was a “an Outperform”.

Analyzing AGIO Stock Performance

On last trading session,, Agios Pharmaceuticals Inc [NASDAQ: AGIO] rose 7.69% to $39.07. The stock’s lowest price that day was $36.6, but it reached a high of $39.1 in the same session. During the last five days, there has been a surge of approximately 13.67%. Over the course of the year, Agios Pharmaceuticals Inc shares have dropped approximately -8.39%. Shares of the company reached a 52-week high of $39.10 on 07/09/25 and a 52-week low of $23.42 on 04/09/25.

Support And Resistance Levels for Agios Pharmaceuticals Inc (AGIO)

According to the 24-hour chart, there is a support level at 37.41, which, if violated, would cause prices to drop to 35.76. In the upper region, resistance lies at 39.91. The next price resistance is at 40.76. RSI (Relative Strength Index) is 71.99 on the 14-day chart, showing overbought technical sentiment.

Is Agios Pharmaceuticals Inc subject to short interest?

Stocks of Agios Pharmaceuticals Inc saw a sharp rise in short interest on 2025-06-13 jumping by 0.17 million shares to 4.32 million. Data from Yahoo Finance shows that the short interest on 2025-05-15 was 4.16 million shares. A jump of 3.83% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 7.43 of the overall float, the days-to-cover ratio (short ratio) jumped to 7.43.

Which companies own the most shares of Agios Pharmaceuticals Inc (AGIO)?

In terms of Agios Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 71 in the next 12 months, up nearly 95.7% from the previous closing price of $36.28. Analysts anticipate Agios Pharmaceuticals Inc stock to reach 71 by 2025, with the lowest price target being 71. In spite of this, 5 analysts ranked Agios Pharmaceuticals Inc stock as Buy at the end of 2025.

Most Popular

Knox Daily
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.