ZYME’s short interest shows a sharp rise on 2025-06-13

The buying and selling of stock by a company’s insider give investors a sense that the stock will rise or fall in the future. Zymeworks BC Inc shares valued at $565,847 were purchased by EcoR1 Capital, LLC on May 15 ’25. At $11.43 per share, EcoR1 Capital, LLC acquired 49,502 shares. The insider’s holdings grew to 17,877,989 shares worth approximately $244.21 million following the completion of this transaction.

Also, EcoR1 Capital, LLC purchased 5,919 shares, netting a total of over 69,738 in proceeds. Following the buying of shares at $11.78 each, the insider now holds 17,883,908 shares.

Before that, EcoR1 Capital, LLC had added 73,953 shares to its account. In a trade valued at $825,589, the Director bought Zymeworks BC Inc shares for $11.16 each. Upon closing the transaction, the insider’s holdings increased to 73,953 shares, worth approximately $242.79 million.

As published in their initiating research note from TD Cowen on May 20, 2025, Zymeworks BC Inc [ZYME] has been a Buy. Analysts at JP Morgan upgraded the stock from ‘”a Neutral”‘ to ‘”an Overweight”‘ outlook in a report released in mid December. As of November 07, 2024, Leerink Partners has increased its “Market perform” rating to a “an Outperform” for ZYME. Earlier on November 01, 2024, Wells Fargo downgraded its rating. Their new recommendation was “an Equal weight” for ZYME stock which previously was a “an Overweight”.

Analyzing ZYME Stock Performance

On last trading session,, Zymeworks BC Inc [NASDAQ: ZYME] rose 0.66% to $13.66. The stock’s lowest price that day was $13.43, but it reached a high of $13.7 in the same session. During the last five days, there has been a surge of approximately 5.97%. Over the course of the year, Zymeworks BC Inc shares have jumped approximately 52.80%. Shares of the company reached a 52-week high of $17.07 on 01/03/25 and a 52-week low of $9.03 on 04/10/25.

Support And Resistance Levels for Zymeworks BC Inc (ZYME)

According to the 24-hour chart, there is a support level at 13.49, which, if violated, would cause prices to drop to 13.33. In the upper region, resistance lies at 13.76. The next price resistance is at 13.87. RSI (Relative Strength Index) is 66.02 on the 14-day chart, showing neutral technical sentiment.

Is Zymeworks BC Inc subject to short interest?

Stocks of Zymeworks BC Inc saw a sharp rise in short interest on 2025-06-13 jumping by 91667.0 shares to 6.88 million. Data from Yahoo Finance shows that the short interest on 2025-05-15 was 6.79 million shares. A jump of 1.33% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 16.57 of the overall float, the days-to-cover ratio (short ratio) jumped to 16.57.

Which companies own the most shares of Zymeworks BC Inc (ZYME)?

In terms of Zymeworks BC Inc share price expectations, FactSet research, analysts set an average price target of 12 in the next 12 months, down nearly -11.57% from the previous closing price of $13.57. Analysts anticipate Zymeworks BC Inc stock to reach 28 by 2025, with the lowest price target being 11. In spite of this, 4 analysts ranked Zymeworks BC Inc stock as Buy at the end of 2025. On March 21, 2023, Wells Fargo assigned a price target of “an Overweight” to the stock and resumed coverage with a $12.

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