IONS (Ionis Pharmaceuticals Inc) may reap gains as insiders became active recently

Ionis Pharmaceuticals Inc’s recent filing unveils that its Chief Executive Officer Monia Brett P unloaded Company’s shares for reported $48416.0 on Jul 11 ’25. In the deal valued at $41.74 per share,1,160 shares were sold. As a result of this transaction, Monia Brett P now holds 179,820 shares worth roughly $7.4 million.

Then, Hayden Michael R bought 15,000 shares, generating $477,900 in total proceeds. Upon buying the shares at $31.86, the Director now owns 50,219 shares.

Before that, Birchler Brian sold 680 shares. Ionis Pharmaceuticals Inc shares valued at $19,292 were divested by the EVP, Corp and Development Ops at a price of $28.37 per share. As a result of the transaction, Birchler Brian now holds 56,660 shares, worth roughly $2.33 million.

Barclays upgraded its Ionis Pharmaceuticals Inc [IONS] rating to an Overweight from a an Equal weight in a research note published recently. A number of analysts have revised their coverage, including H.C. Wainwright’s analysts, who began to cover the stock in early April with a ‘”a Buy”‘ rating. Redburn Atlantic began covering IONS with “Neutral” recommendation on March 31, 2025. BMO Capital Markets revised its rating on August 02, 2024. It rated IONS as “a Market perform” which previously was an “an Outperform”.

Price Performance Review of IONS

On Monday, Ionis Pharmaceuticals Inc [NASDAQ:IONS] saw its stock fall -2.54% to $41.17. Over the last five days, the stock has lost -0.91%. Ionis Pharmaceuticals Inc shares have fallen nearly -18.86% since the year began. Nevertheless, the stocks have risen 17.76% over the past one year. While a 52-week high of $52.34 was reached on 07/02/25, a 52-week low of $23.95 was recorded on 04/09/25.

Levels Of Support And Resistance For IONS Stock

The 24-hour chart illustrates a support level at 40.72, which if violated will result in even more drops to 40.26. On the upside, there is a resistance level at 42.06. A further resistance level may holdings at 42.94.

How much short interest is there in Ionis Pharmaceuticals Inc?

A steep rise in short interest was recorded in Ionis Pharmaceuticals Inc stocks on 2025-07-15, dropping by -1.34 million shares to a total of 12.89 million shares. Yahoo Finance data shows the prior-month short interest on 2025-06-13 was 14.23 million shares. There was a decline of -10.37%, which implies that there is a negative sentiment for the stock.

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