AXSM price target predicted to rise nearly 189 in 12 months

Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Axsome Therapeutics Inc shares valued at $2,446,052 were purchased by JEFFS ROGER on Aug 27 ’25. At $122.30 per share, JEFFS ROGER acquired 20,000 shares.

Also, JEFFS ROGER sold 20,000 shares, netting a total of over 2,400,600 in proceeds. Following the sale of shares at $120.03 each, the insider now holds 130,974 shares.

Before that, JEFFS ROGER had sold 16,694 shares from its account. In a trade valued at $2,004,616, the Director traded Axsome Therapeutics Inc shares for $120.08 each. Upon closing the transaction, the insider’s holdings decreased to 16,694 shares, worth approximately $18.4 million.

Analysts at Oppenheimer started covering the stock with ‘”an Outperform”‘ outlook in a report released in early June. As of April 07, 2025, Jefferies has initiated its “Buy” rating for AXSM. Earlier on February 11, 2025, Deutsche Bank initiated its rating. Their recommendation was “a Buy” for AXSM stock.

Analyzing AXSM Stock Performance

On last trading session, Axsome Therapeutics Inc [NASDAQ: AXSM] rose 0.59% to $121.86. The stock’s lowest price that day was $120.48, but it reached a high of $123.59 in the same session. During the last five days, there has been a surge of approximately 4.16%. Over the course of the year, Axsome Therapeutics Inc shares have jumped approximately 38.49%. Shares of the company reached a 52-week high of $139.13 on 02/21/25 and a 52-week low of $79.19 on 01/10/25.

Support And Resistance Levels for Axsome Therapeutics Inc (AXSM)

According to the 24-hour chart, there is a support level at 120.36, which, if violated, would cause prices to drop to 118.87. In the upper region, resistance lies at 123.47. The next price resistance is at 125.09. RSI (Relative Strength Index) is 72.58 on the 14-day chart, showing overbought technical sentiment.

Is Axsome Therapeutics Inc subject to short interest?

Stocks of Axsome Therapeutics Inc saw a sharp rise in short interest on 2025-08-15 jumping by 91211.0 shares to 3.72 million. Data from Yahoo Finance shows that the short interest on 2025-07-15 was 3.63 million shares. A jump of 2.45% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 6.11 of the overall float, the days-to-cover ratio (short ratio) jumped to 6.11.

Which companies own the most shares of Axsome Therapeutics Inc (AXSM)?

In terms of Axsome Therapeutics Inc share price expectations, FactSet research, analysts set an average price target of 189 in the next 12 months, up nearly 56.0% from the previous closing price of $121.15. Analysts anticipate Axsome Therapeutics Inc stock to reach 216 by 2025, with the lowest price target being 162. In spite of this, 15 analysts ranked Axsome Therapeutics Inc stock as Buy at the end of 2025. On December 31, 2024, Mizuho assigned a price target of “an Outperform” to the stock and reiterated coverage with a $122.

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