Short interest on ANAB sees a significant decrease on 2025-09-15

The buying and selling of stock by a company’s insider give investors a sense that the stock will rise or fall in the future. AnaptysBio Inc shares valued at $238,960 were sold by LOUMEAU ERIC J on Sep 30 ’25. At $29.00 per share, LOUMEAU ERIC J sold 8,240 shares. The insider’s holdings dropped to 9,088 shares worth approximately $0.29 million following the completion of this transaction.

Also, ERIC J LOUMEAU purchased 8,240 shares, netting a total of over 238,960 in proceeds.

Before that, RENTON HOLLINGS had sold 10,231 shares from its account. In a trade valued at $200,714, the Director traded AnaptysBio Inc shares for $19.62 each. Upon closing the transaction, the insider’s holdings decreased to 10,231 shares, worth approximately $0.16 million.

As published in a research note from H.C. Wainwright on June 04, 2025, AnaptysBio Inc [ANAB] has been rated up from a Neutral to a Buy and the price target has been revised to $38. Analysts at Wolfe Research started covering the stock with ‘”an Outperform”‘ outlook in a report released in early February. As of December 11, 2024, H.C. Wainwright has decreased its “Buy” rating to a “Neutral” for ANAB. Earlier on December 02, 2024, BTIG Research downgraded its rating. Their new recommendation was “a Neutral” for ANAB stock which previously was a “a Buy”.

Analyzing ANAB Stock Performance

On last trading session, AnaptysBio Inc [NASDAQ: ANAB] rose 6.56% to $31.83. The stock’s lowest price that day was $30.2701, but it reached a high of $31.99 in the same session. During the last five days, there has been a drop of approximately -0.44%. Over the course of the year, AnaptysBio Inc shares have dropped approximately -6.33%. Shares of the company reached a 52-week high of $33.48 on 10/01/25 and a 52-week low of $12.21 on 02/11/25.

Support And Resistance Levels for AnaptysBio Inc (ANAB)

According to the 24-hour chart, there is a support level at 30.74, which, if violated, would cause prices to drop to 29.64. In the upper region, resistance lies at 32.46. The next price resistance is at 33.08. RSI (Relative Strength Index) is 72.63 on the 14-day chart, showing overbought technical sentiment.

Is AnaptysBio Inc subject to short interest?

Stocks of AnaptysBio Inc saw a sharp steep in short interest on 2025-09-15 dropping by -0.18 million shares to 9.41 million. Data from Yahoo Finance shows that the short interest on 2025-08-15 was 9.6 million shares. A decline of -1.96% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 20.71 of the overall float, the days-to-cover ratio (short ratio) decline to 20.71.

Which companies own the most shares of AnaptysBio Inc (ANAB)?

In terms of AnaptysBio Inc share price expectations, FactSet research, analysts set an average price target of 56.5 in the next 12 months, up nearly 89.15% from the previous closing price of $29.87. Analysts anticipate AnaptysBio Inc stock to reach 59 by 2025, with the lowest price target being 54. In spite of this, 6 analysts ranked AnaptysBio Inc stock as Buy at the end of 2025. On July 22, 2024, H.C. Wainwright assigned a price target of “a Buy” to the stock and initiated coverage with a $55.

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