Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Amylyx Pharmaceuticals Inc shares valued at $430,952 were sold by Klee Justin B. on Sep 30 ’25. At $14.38 per share, Klee Justin B. sold 29,975 shares. The insider’s holdings dropped to 3,325,301 shares worth approximately $48.12 million following the completion of this transaction.
Also, Mazzariello Gina sold 8,828 shares, netting a total of over 128,669 in proceeds. Following the sale of shares at $14.58 each, the insider now holds 148,141 shares.
Before that, FRATES JAMES M had sold 10,558 shares from its account. In a trade valued at $154,650, the Chief Financial Officer traded Amylyx Pharmaceuticals Inc shares for $14.65 each. Upon closing the transaction, the insider’s holdings decreased to 10,558 shares, worth approximately $4.06 million.
Analysts at Guggenheim started covering the stock with ‘”a Buy”‘ outlook in a report released in late June. As of June 17, 2025, Citigroup has initiated its “Buy” rating for AMLX. Earlier on May 30, 2025, TD Cowen initiated its rating. Their recommendation was “a Buy” for AMLX stock.
Analyzing AMLX Stock Performance
On last trading session, Amylyx Pharmaceuticals Inc [NASDAQ: AMLX] rose 7.34% to $14.47. The stock’s lowest price that day was $13.33, but it reached a high of $15.16 in the same session. During the last five days, there has been a surge of approximately 8.88%. Over the course of the year, Amylyx Pharmaceuticals Inc shares have jumped approximately 369.81%. Shares of the company reached a 52-week high of $15.16 on 10/09/25 and a 52-week low of $2.60 on 03/04/25.
Support And Resistance Levels for Amylyx Pharmaceuticals Inc (AMLX)
According to the 24-hour chart, there is a support level at 13.48, which, if violated, would cause prices to drop to 12.49. In the upper region, resistance lies at 15.31. The next price resistance is at 16.15. RSI (Relative Strength Index) is 66.07 on the 14-day chart, showing neutral technical sentiment.
Is Amylyx Pharmaceuticals Inc subject to short interest?
Stocks of Amylyx Pharmaceuticals Inc saw a sharp rise in short interest on 2025-09-15 jumping by 1.34 million shares to 8.77 million. Data from Yahoo Finance shows that the short interest on 2025-08-15 was 7.43 million shares. A jump of 15.29% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 4.68 of the overall float, the days-to-cover ratio (short ratio) jumped to 4.68.
Which companies own the most shares of Amylyx Pharmaceuticals Inc (AMLX)?
In terms of Amylyx Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 17.5 in the next 12 months, up nearly 29.82% from the previous closing price of $13.48. Analysts anticipate Amylyx Pharmaceuticals Inc stock to reach 25 by 2025, with the lowest price target being 10. In spite of this, 3 analysts ranked Amylyx Pharmaceuticals Inc stock as Buy at the end of 2025. On April 07, 2025, Mizuho assigned a price target of “an Outperform” to the stock and upgraded coverage with a $7.
