Ionis Pharmaceuticals Inc (IONS) receives an Overweight rating from JP Morgan

Samantha Gray

Ionis Pharmaceuticals Inc’s recently made public that its EVP Research Swayze Eric unloaded Company’s shares for reported $3902.0 on Oct 16 ’25. In the deal valued at $73.62 per share,53 shares were sold. As a result of this transaction, Swayze Eric now holds 256 shares worth roughly $18685.44.

Then, PARSHALL B LYNNE sold 5,000 shares, generating $358,722 in total proceeds. Upon selling the shares at $71.74, the Director now owns 61,344 shares.

Before that, Devers Shannon L. sold 6,000 shares. Ionis Pharmaceuticals Inc shares valued at $437,654 were divested by the EVP, Chief Human Resources Ofc at a price of $72.94 per share. As a result of the transaction, Devers Shannon L. now holds 15,937 shares, worth roughly $1.16 million.

JP Morgan upgraded its Ionis Pharmaceuticals Inc [IONS] rating to an Overweight from a a Neutral in a research note published recently. A number of analysts have revised their coverage, including Goldman’s analysts, who increased its forecast for the stock in late September from “a Sell” to “a Neutral”. BMO Capital Markets also remained covering IONS and has increased its forecast on September 03, 2025 with a “an Outperform” recommendation from previously “Market perform” rating. Morgan Stanley revised its rating on July 31, 2025. It rated IONS as “an Overweight” which previously was an “an Equal-weight”.

Price Performance Review of IONS

On Monday, Ionis Pharmaceuticals Inc [NASDAQ:IONS] saw its stock jump 3.01% to $72.99. Over the last five days, the stock has lost -0.76%. Ionis Pharmaceuticals Inc shares have risen nearly 89.98% since the year began. Nevertheless, the stocks have risen 108.78% over the past one year. While a 52-week high of $74.42 was reached on 10/16/25, a 52-week low of $23.95 was recorded on 04/09/25.

Levels Of Support And Resistance For IONS Stock

The 24-hour chart illustrates a support level at 71.88, which if violated will result in even more drops to 70.76. On the upside, there is a resistance level at 73.69. A further resistance level may holdings at 74.38.

How much short interest is there in Ionis Pharmaceuticals Inc?

A steep rise in short interest was recorded in Ionis Pharmaceuticals Inc stocks on 2025-10-15, growing by 1.73 million shares to a total of 13.7 million shares. Yahoo Finance data shows the prior-month short interest on 2025-09-15 was 11.97 million shares. There was a rise of 12.6%, which implies that there is a positive sentiment for the stock.

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