Ionis Pharmaceuticals Inc’s filing revealed that its EVP, Corp and Development Ops Birchler Brian unloaded Company’s shares for reported $0.61 million on Nov 06 ’25. In the deal valued at $76.17 per share,8,000 shares were sold. As a result of this transaction, Birchler Brian now holds 48,826 shares worth roughly $3.59 million.
Then, Geary Richard S sold 33,038 shares, generating $2,501,725 in total proceeds. Upon selling the shares at $75.72, the EVP, Chief Development Officer now owns 59,657 shares.
Before that, Geary Richard S sold 1,601 shares. Ionis Pharmaceuticals Inc shares valued at $120,091 were divested by the EVP, Chief Development Officer at a price of $75.01 per share. As a result of the transaction, Geary Richard S now holds 59,657 shares, worth roughly $4.39 million.
JP Morgan upgraded its Ionis Pharmaceuticals Inc [IONS] rating to an Overweight from a a Neutral in a research note published recently. A number of analysts have revised their coverage, including Goldman’s analysts, who increased its forecast for the stock in late September from “a Sell” to “a Neutral”. BMO Capital Markets also remained covering IONS and has increased its forecast on September 03, 2025 with a “an Outperform” recommendation from previously “Market perform” rating. Morgan Stanley revised its rating on July 31, 2025. It rated IONS as “an Overweight” which previously was an “an Equal-weight”.
Price Performance Review of IONS
On Friday, Ionis Pharmaceuticals Inc [NASDAQ:IONS] saw its stock fall -0.74% to $73.55. Over the last five days, the stock has lost -1.01%. Ionis Pharmaceuticals Inc shares have risen nearly 89.56% since the year began. Nevertheless, the stocks have risen 110.38% over the past one year. While a 52-week high of $76.78 was reached on 11/06/25, a 52-week low of $23.95 was recorded on 04/09/25.
Levels Of Support And Resistance For IONS Stock
The 24-hour chart illustrates a support level at 72.27, which if violated will result in even more drops to 71.00. On the upside, there is a resistance level at 74.91. A further resistance level may holdings at 76.28.
How much short interest is there in Ionis Pharmaceuticals Inc?
A steep rise in short interest was recorded in Ionis Pharmaceuticals Inc stocks on 2025-10-15, growing by 1.73 million shares to a total of 13.7 million shares. Yahoo Finance data shows the prior-month short interest on 2025-09-15 was 11.97 million shares. There was a rise of 12.6%, which implies that there is a positive sentiment for the stock.
