Annovis Bio Inc [ANVS] Investment Guide: What You Need to Know

Roman Campbell

In a filing, Annovis Bio Inc revealed its President & CEO Maccecchini Maria-Luisa acquired Company’s shares for reported $0.2 million on Oct 28 ’25. In the deal valued at $2.05 per share,97,561 shares were bought. As a result of this transaction, Maccecchini Maria-Luisa now holds 1,212,020 shares worth roughly $2.84 million.

Then, Hoffman Michael B bought 975,610 shares, generating $2,000,000 in total proceeds. Upon buying the shares at $2.05, the Director now owns 2,455,539 shares.

D. Boral Capital downgraded its Annovis Bio Inc [ANVS] rating to a Hold from a a Buy in a research note published recently. A number of analysts have revised their coverage, including Maxim Group’s analysts, who increased its forecast for the stock in late October from “a Hold” to “a Buy”. Canaccord Genuity began covering ANVS with “Buy” recommendation on December 29, 2023. Maxim Group maintained its rating on July 07, 2021. It rated ANVS as “a Buy”.

Price Performance Review of ANVS

On Friday, Annovis Bio Inc [NYSE:ANVS] saw its stock jump 2.18% to $2.34. Over the last five days, the stock has gained 17.00%. Annovis Bio Inc shares have fallen nearly -68.97% since the year began. Nevertheless, the stocks have fallen -53.48% over the past one year. While a 52-week high of $7.52 was reached on 01/03/25, a 52-week low of $1.11 was recorded on 04/09/25.

Levels Of Support And Resistance For ANVS Stock

The 24-hour chart illustrates a support level at 2.16, which if violated will result in even more drops to 1.98. On the upside, there is a resistance level at 2.47. A further resistance level may holdings at 2.61.

How much short interest is there in Annovis Bio Inc?

A steep rise in short interest was recorded in Annovis Bio Inc stocks on 2025-10-31, dropping by -0.37 million shares to a total of 1.03 million shares. Yahoo Finance data shows the prior-month short interest on 2025-09-30 was 1.4 million shares. There was a decline of -35.36%, which implies that there is a negative sentiment for the stock.

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