CSTL short interest declines, indicating growing optimism among investors

Samantha Gray

Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Castle Biosciences Inc shares valued at $91,106 were sold by MAETZOLD DEREK J on Nov 18 ’25. At $34.02 per share, MAETZOLD DEREK J sold 2,678 shares. The insider’s holdings dropped to 50,937 shares worth approximately $1.82 million following the completion of this transaction.

Also, Stokes Frank sold 5,388 shares, netting a total of over 189,011 in proceeds. Following the sale of shares at $35.08 each, the insider now holds 43,328 shares.

Before that, Juvenal Tobin W had sold 500 shares from its account. In a trade valued at $17,695, the Chief Commercial Officer traded Castle Biosciences Inc shares for $35.39 each. Upon closing the transaction, the insider’s holdings decreased to 500 shares, worth approximately $3.0 million.

As published in their initiating research note from Guggenheim on December 14, 2023, Castle Biosciences Inc [CSTL] has been a Buy and the price target has been revised to $25. Analysts at Scotiabank started covering the stock with ‘”a Sector outperform”‘ outlook in a report released in early January. As of January 07, 2022, Stephens has initiated its “an Overweight” rating for CSTL. Earlier on April 30, 2021, Lake Street initiated its rating. Their recommendation was “a Buy” for CSTL stock.

Analyzing CSTL Stock Performance

On last trading session, Castle Biosciences Inc [NASDAQ: CSTL] rose 3.09% to $35.72. The stock’s lowest price that day was $34.92, but it reached a high of $36.598 in the same session. During the last five days, there has been a surge of approximately 4.69%. Over the course of the year, Castle Biosciences Inc shares have jumped approximately 28.03%. Shares of the company reached a 52-week high of $36.60 on 11/20/25 and a 52-week low of $14.59 on 08/04/25.

Support And Resistance Levels for Castle Biosciences Inc (CSTL)

According to the 24-hour chart, there is a support level at 34.89, which, if violated, would cause prices to drop to 34.07. In the upper region, resistance lies at 36.57. The next price resistance is at 37.42. RSI (Relative Strength Index) is 77.28 on the 14-day chart, showing overbought technical sentiment.

Is Castle Biosciences Inc subject to short interest?

Stocks of Castle Biosciences Inc saw a sharp steep in short interest on 2025-10-31 dropping by 7460.0 shares to 1.55 million. Data from Yahoo Finance shows that the short interest on 2025-09-30 was 1.55 million shares. A decline of -0.48% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 5.8 of the overall float, the days-to-cover ratio (short ratio) decline to 5.8.

Which companies own the most shares of Castle Biosciences Inc (CSTL)?

In terms of Castle Biosciences Inc share price expectations, FactSet research, analysts set an average price target of 37 in the next 12 months, up nearly 6.78% from the previous closing price of $34.65. Analysts anticipate Castle Biosciences Inc stock to reach 45 by 2025, with the lowest price target being 30. In spite of this, 3 analysts ranked Castle Biosciences Inc stock as Buy at the end of 2025. On November 10, 2020, KeyBanc Capital Markets assigned a price target of “an Overweight” to the stock and initiated coverage with a $70.

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