Short interest on AMGN sees a significant increase on 2025-10-31

Daniel Torres

The buying and selling of stock by a company’s insider give investors a sense that the stock will rise or fall in the future. AMGEN Inc shares valued at $1,058,667 were purchased by Grygiel Nancy A. on Nov 20 ’25. At $337.26 per share, Grygiel Nancy A. acquired 3,139 shares.

Also, Khosla Rachna sold 890 shares, netting a total of over 299,256 in proceeds. Following the sale of shares at $336.24 each, the insider now holds 7,082 shares.

Before that, Gordon Murdo had sold 6,879 shares from its account. In a trade valued at $2,317,071, the EVP, Global Commercial Ops traded AMGEN Inc shares for $336.83 each. Upon closing the transaction, the insider’s holdings decreased to 6,879 shares, worth approximately $14.09 million.

As published in their initiating research note from Scotiabank on November 13, 2025, AMGEN Inc [AMGN] has been a Sector outperform and the price target has been revised to $385.

Analyzing AMGN Stock Performance

On last trading session, AMGEN Inc [NASDAQ: AMGN] plunged -1.85% to $336.07. The stock’s lowest price that day was $335.0, but it reached a high of $345.09 in the same session. During the last five days, there has been a surge of approximately 0.02%. Over the course of the year, AMGEN Inc shares have jumped approximately 20.56%. Shares of the company reached a 52-week high of $345.84 on 11/13/25 and a 52-week low of $257.05 on 01/06/25.

Support And Resistance Levels for AMGEN Inc (AMGN)

According to the 24-hour chart, there is a support level at 332.35, which, if violated, would cause prices to drop to 328.63. In the upper region, resistance lies at 342.44. The next price resistance is at 348.81. RSI (Relative Strength Index) is 67.91 on the 14-day chart, showing neutral technical sentiment.

Is AMGEN Inc subject to short interest?

Stocks of AMGEN Inc saw a sharp rise in short interest on 2025-10-31 jumping by 0.52 million shares to 13.43 million. Data from Yahoo Finance shows that the short interest on 2025-09-30 was 12.91 million shares. A jump of 3.86% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 6.11 of the overall float, the days-to-cover ratio (short ratio) jumped to 6.11.

Which companies own the most shares of AMGEN Inc (AMGN)?

In terms of AMGEN Inc share price expectations, FactSet research, analysts set an average price target of 315 in the next 12 months, down nearly -8.0% from the previous closing price of $342.4. Analysts anticipate AMGEN Inc stock to reach 381 by 2025, with the lowest price target being 300. In spite of this, 19 analysts ranked AMGEN Inc stock as Buy at the end of 2025. On December 10, 2024, BofA Securities assigned a price target of “an Underperform” to the stock and resumed coverage with a $256.

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