Investors can expect a company’s stock to rise or fall based on the buying and selling of stock by its insiders. Praxis Precision Medicines Inc shares valued at $4,852,256 were sold by Nemiroff Alex on Nov 20 ’25. At $193.09 per share, Nemiroff Alex sold 25,130 shares. The insider’s holdings dropped to 20,832 shares worth approximately $3.88 million following the completion of this transaction.
Also, Mastrocola Lauren sold 13,600 shares, netting a total of over 2,612,244 in proceeds. Following the sale of shares at $192.08 each, the insider now holds 10,442 shares.
Before that, Nemiroff Alex had added 25,130 shares to its account. In a trade valued at $4,852,249, the Officer bought Praxis Precision Medicines Inc shares for $193.09 each.
As published in their initiating research note from BTIG Research on November 19, 2025, Praxis Precision Medicines Inc [PRAX] has been a Buy and the price target has been revised to $424. As of May 07, 2025, Chardan Capital Markets has initiated its “Buy” rating for PRAX. Earlier on March 03, 2025, H.C. Wainwright resumed its rating. Their recommendation was “a Buy” for PRAX stock.
Analyzing PRAX Stock Performance
On last trading session, Praxis Precision Medicines Inc [NASDAQ: PRAX] rose 3.93% to $186.15. The stock’s lowest price that day was $180.46, but it reached a high of $190.755 in the same session. During the last five days, there has been a surge of approximately 1.03%. Over the course of the year, Praxis Precision Medicines Inc shares have jumped approximately 132.19%. Shares of the company reached a 52-week high of $206.71 on 10/30/25 and a 52-week low of $26.70 on 04/09/25.
Support And Resistance Levels for Praxis Precision Medicines Inc (PRAX)
According to the 24-hour chart, there is a support level at 180.82, which, if violated, would cause prices to drop to 175.49. In the upper region, resistance lies at 191.12. The next price resistance is at 196.08. RSI (Relative Strength Index) is 55.73 on the 14-day chart, showing neutral technical sentiment.
Is Praxis Precision Medicines Inc subject to short interest?
Stocks of Praxis Precision Medicines Inc saw a sharp rise in short interest on 2025-11-14 jumping by 1.0 million shares to 3.61 million. Data from Yahoo Finance shows that the short interest on 2025-10-15 was 2.61 million shares. A jump of 27.72% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 2.49 of the overall float, the days-to-cover ratio (short ratio) jumped to 2.49.
Which companies own the most shares of Praxis Precision Medicines Inc (PRAX)?
In terms of Praxis Precision Medicines Inc share price expectations, FactSet research, analysts set an average price target of 315 in the next 12 months, up nearly 75.86% from the previous closing price of $179.12. Analysts anticipate Praxis Precision Medicines Inc stock to reach 540 by 2025, with the lowest price target being 115. In spite of this, 5 analysts ranked Praxis Precision Medicines Inc stock as Buy at the end of 2025. On February 11, 2025, Deutsche Bank assigned a price target of “a Buy” to the stock and initiated coverage with a $111.
