A company insider recently bought 45,000 shares of Annovis Bio Inc [ANVS]. Should You Buy?

Samantha Gray

The buying and selling of stock by a company’s insider give investors a sense that the stock will rise or fall in the future. Annovis Bio Inc shares valued at $193,794 were purchased by Hoffman Michael B on Dec 08 ’25. At $4.31 per share, Hoffman Michael B acquired 45,000 shares. The insider’s holdings grew to 2,574,739 shares worth approximately $10.48 million following the completion of this transaction.

Also, Hoffman Michael B purchased 39,200 shares, netting a total of over 159,886 in proceeds. Following the buying of shares at $4.08 each, the insider now holds 2,519,739 shares.

Before that, Hoffman Michael B had added 20,000 shares to its account. In a trade valued at $69,900, the Director bought Annovis Bio Inc shares for $3.50 each. Upon closing the transaction, the insider’s holdings increased to 20,000 shares, worth approximately $10.14 million.

As published in a research note from D. Boral Capital on February 10, 2025, Annovis Bio Inc [ANVS] has been rated down from a Buy to a Hold. Analysts at Maxim Group upgraded the stock from ‘”a Hold”‘ to ‘”a Buy”‘ outlook in a report released in late October. As of December 29, 2023, Canaccord Genuity has initiated its “Buy” rating for ANVS. Earlier on July 07, 2021, Maxim Group resumed its rating. Their recommendation was “a Buy” for ANVS stock.

Analyzing ANVS Stock Performance

On last trading session, Annovis Bio Inc [NYSE: ANVS] rose 5.71% to $4.07. The stock’s lowest price that day was $3.88, but it reached a high of $4.1164 in the same session. During the last five days, there has been a surge of approximately 17.63%. Over the course of the year, Annovis Bio Inc shares have dropped approximately -24.49%. Shares of the company reached a 52-week high of $4.12 on 01/07/26 and a 52-week low of $3.26 on 01/02/26.

Support And Resistance Levels for Annovis Bio Inc (ANVS)

According to the 24-hour chart, there is a support level at 3.93, which, if violated, would cause prices to drop to 3.79. In the upper region, resistance lies at 4.16. The next price resistance is at 4.26. RSI (Relative Strength Index) is 58.08 on the 14-day chart, showing neutral technical sentiment.

Is Annovis Bio Inc subject to short interest?

Stocks of Annovis Bio Inc saw a sharp rise in short interest on 2025-12-15 jumping by 1.54 million shares to 2.86 million. Data from Yahoo Finance shows that the short interest on 2025-11-14 was 1.31 million shares. A jump of 54.01% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 0.71 of the overall float, the days-to-cover ratio (short ratio) jumped to 0.71.

Which companies own the most shares of Annovis Bio Inc (ANVS)?

In terms of Annovis Bio Inc share price expectations, FactSet research, analysts set an average price target of 26 in the next 12 months, up nearly 575.32% from the previous closing price of $3.85. Analysts anticipate Annovis Bio Inc stock to reach 30 by 2026, with the lowest price target being 21. In spite of this, 2 analysts ranked Annovis Bio Inc stock as Buy at the end of 2026.

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