Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Jazz Pharmaceuticals plc shares valued at $379,366 were sold by Henderson Mary Elizabeth on Dec 09 ’25. At $169.51 per share, Henderson Mary Elizabeth sold 2,238 shares. The insider’s holdings dropped to 19,508 shares worth approximately $3.3 million following the completion of this transaction.
Also, MARY ELIZABETH HENDERSON purchased 2,238 shares, netting a total of over 379,365 in proceeds.
Before that, Carr Patricia had sold 4,660 shares from its account. In a trade valued at $797,783, the SVP, Chief Accounting Officer traded Jazz Pharmaceuticals plc shares for $171.20 each. Upon closing the transaction, the insider’s holdings decreased to 4,660 shares, worth approximately $1.19 million.
As published in a research note from UBS on November 24, 2025, Jazz Pharmaceuticals plc [JAZZ] has been rated down from a Buy to a Neutral and the price target has been revised to $188. Analysts at Deutsche Bank started covering the stock with ‘”a Buy”‘ outlook in a report released in mid July. As of March 07, 2025, UBS has increased its “Neutral” rating to a “Buy” for JAZZ. Earlier on February 26, 2025, Cantor Fitzgerald downgraded its rating. Their new recommendation was “a Neutral” for JAZZ stock which previously was a “an Overweight”.
Analyzing JAZZ Stock Performance
On last trading session, Jazz Pharmaceuticals plc [NASDAQ: JAZZ] rose 0.76% to $169.16. The stock’s lowest price that day was $167.125, but it reached a high of $170.42 in the same session. During the last five days, there has been a surge of approximately 4.14%. Over the course of the year, Jazz Pharmaceuticals plc shares have jumped approximately 39.59%.
Is Jazz Pharmaceuticals plc subject to short interest?
Stocks of Jazz Pharmaceuticals plc saw a sharp rise in short interest on 2025-12-31 jumping by 0.39 million shares to 5.36 million. Data from Yahoo Finance shows that the short interest on 2025-11-28 was 4.97 million shares. A jump of 7.24% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 5.72 of the overall float, the days-to-cover ratio (short ratio) jumped to 5.72.
Which companies own the most shares of Jazz Pharmaceuticals plc (JAZZ)?
In terms of Jazz Pharmaceuticals plc share price expectations, FactSet research, analysts set an average price target of 205 in the next 12 months, up nearly 22.11% from the previous closing price of $167.88. Analysts anticipate Jazz Pharmaceuticals plc stock to reach 235 by 2026, with the lowest price target being 170. In spite of this, 6 analysts ranked Jazz Pharmaceuticals plc stock as Buy at the end of 2026. On February 13, 2025, Wells Fargo assigned a price target of “an Overweight” to the stock and upgraded coverage with a $170.






