Negative sentiment towards AMGN reflected by a jump of 4.38% in short interest

Roman Campbell

Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. AMGEN Inc shares valued at $1,058,667 were sold by Grygiel Nancy A. on Nov 20 ’25. At $337.26 per share, Grygiel Nancy A. sold 3,139 shares. The insider’s holdings dropped to 7,225 shares worth approximately $2.51 million following the completion of this transaction.

Also, Grygiel Nancy A. purchased 3,139 shares, netting a total of over 1,058,667 in proceeds.

Before that, Khosla Rachna had sold 890 shares from its account. In a trade valued at $299,256, the SVP, Business Development traded AMGEN Inc shares for $336.24 each. Upon closing the transaction, the insider’s holdings decreased to 890 shares, worth approximately $2.46 million.

As published in a research note from Bernstein on January 20, 2026, AMGEN Inc [AMGN] has been rated down from an Outperform to a Mkt perform and the price target has been revised to $335. As of December 05, 2025, Erste Group has increased its “Hold” rating to a “Buy” for AMGN.

Analyzing AMGN Stock Performance

On last trading session, AMGEN Inc [NASDAQ: AMGN] rose 1.01% to $347.07. The stock’s lowest price that day was $342.21, but it reached a high of $349.98 in the same session. During the last five days, there has been a surge of approximately 5.50%. Over the course of the year, AMGEN Inc shares have jumped approximately 26.29%.

Is AMGEN Inc subject to short interest?

Stocks of AMGEN Inc saw a sharp rise in short interest on 2025-12-31 jumping by 0.66 million shares to 14.98 million. Data from Yahoo Finance shows that the short interest on 2025-11-28 was 14.32 million shares. A jump of 4.38% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 5.13 of the overall float, the days-to-cover ratio (short ratio) jumped to 5.13.

Which companies own the most shares of AMGEN Inc (AMGN)?

In terms of AMGEN Inc share price expectations, FactSet research, analysts set an average price target of 372 in the next 12 months, up nearly 8.27% from the previous closing price of $343.6. Analysts anticipate AMGEN Inc stock to reach 425 by 2026, with the lowest price target being 304. In spite of this, 19 analysts ranked AMGEN Inc stock as Buy at the end of 2026. On November 13, 2025, Scotiabank assigned a price target of “a Sector outperform” to the stock and initiated coverage with a $385.

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