Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Prime Medicine Inc shares valued at $45,402 were purchased by Liu David R. on Jun 23 ’25. At $2.16 per share, Liu David R. acquired 21,000 shares. The insider’s holdings grew to 20,219,945 shares worth approximately $48.93 million following the completion of this transaction.
Also, Liu David R. purchased 21,000 shares, netting a total of over 31,196 in proceeds. Following the buying of shares at $1.49 each, the insider now holds 20,198,945 shares.
Before that, Liu David R. had added 21,000 shares to its account. In a trade valued at $33,590, the 10% Owner bought Prime Medicine Inc shares for $1.60 each. Upon closing the transaction, the insider’s holdings increased to 21,000 shares, worth approximately $48.83 million.
As published in a research note from Citigroup on May 27, 2025, Prime Medicine Inc [PRME] has been rated down from a Buy to a Neutral and the price target has been revised to $1.50. Analysts at JP Morgan downgraded the stock from ‘”an Overweight”‘ to ‘”a Neutral”‘ outlook in a report released in mid May. As of May 20, 2025, H.C. Wainwright has decreased its “Buy” rating to a “Neutral” for PRME. Earlier on December 10, 2024, JMP Securities initiated its rating. Their recommendation was “a Mkt outperform” for PRME stock.
Analyzing PRME Stock Performance
On last trading session,, Prime Medicine Inc [NASDAQ: PRME] plunged -1.63% to $2.42. The stock’s lowest price that day was $2.18, but it reached a high of $2.5151 in the same session. During the last five days, there has been a surge of approximately 49.85%. Over the course of the year, Prime Medicine Inc shares have dropped approximately -59.60%. Shares of the company reached a 52-week high of $3.59 on 01/06/25 and a 52-week low of $1.11 on 05/22/25.
Support And Resistance Levels for Prime Medicine Inc (PRME)
According to the 24-hour chart, there is a support level at 2.23, which, if violated, would cause prices to drop to 2.04. In the upper region, resistance lies at 2.56. The next price resistance is at 2.71. RSI (Relative Strength Index) is 76.54 on the 14-day chart, showing overbought technical sentiment.
Is Prime Medicine Inc subject to short interest?
Stocks of Prime Medicine Inc saw a sharp rise in short interest on 2025-05-30 jumping by 1.44 million shares to 17.97 million. Data from Yahoo Finance shows that the short interest on 2025-04-30 was 16.53 million shares. A jump of 8.01% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 7.67 of the overall float, the days-to-cover ratio (short ratio) jumped to 7.67.
Which companies own the most shares of Prime Medicine Inc (PRME)?
In terms of Prime Medicine Inc share price expectations, FactSet research, analysts set an average price target of 17 in the next 12 months, up nearly 591.06% from the previous closing price of $2.46. Analysts anticipate Prime Medicine Inc stock to reach 23 by 2025, with the lowest price target being 12. In spite of this, 5 analysts ranked Prime Medicine Inc stock as Buy at the end of 2025. On May 20, 2024, H.C. Wainwright assigned a price target of “a Buy” to the stock and initiated coverage with a $10.
