Positive sentiment towards CDXS reflected in decline in short interest

Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Codexis Inc shares valued at $225,710 were purchased by Opaleye Management Inc. on Jul 31 ’25. At $2.68 per share, Opaleye Management Inc. acquired 84,220 shares. The insider’s holdings grew to 12,544,220 shares worth approximately $35.88 million following the completion of this transaction.

Also, Opaleye Management Inc. purchased 780 shares, netting a total of over 2,211 in proceeds. Following the buying of shares at $2.83 each, the insider now holds 12,545,000 shares.

Before that, Opaleye Management Inc. had added 8,422 shares to its account. In a trade valued at $23,750, the 10% Owner bought Codexis Inc shares for $2.82 each. Upon closing the transaction, the insider’s holdings increased to 8,422 shares, worth approximately $35.63 million.

As published in a research note from The Benchmark Company on August 19, 2024, Codexis Inc [CDXS] has been rated down from a Buy to a Hold. As of May 30, 2024, Cantor Fitzgerald has initiated its “an Overweight” rating for CDXS. Earlier on February 29, 2024, The Benchmark Company upgraded its rating. Their new recommendation was “a Buy” for CDXS stock which previously was a “a Hold”.

Analyzing CDXS Stock Performance

On last trading session, Codexis Inc [NASDAQ: CDXS] plunged -2.39% to $2.86. The stock’s lowest price that day was $2.8445, but it reached a high of $2.92 in the same session. During the last five days, there has been a surge of approximately 2.51%. Over the course of the year, Codexis Inc shares have dropped approximately -13.33%.

Is Codexis Inc subject to short interest?

Stocks of Codexis Inc saw a sharp steep in short interest on 2025-07-15 dropping by -0.66 million shares to 5.7 million. Data from Yahoo Finance shows that the short interest on 2025-06-13 was 6.36 million shares. A decline of -11.51% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 5.96 of the overall float, the days-to-cover ratio (short ratio) decline to 5.96.

Which companies own the most shares of Codexis Inc (CDXS)?

In terms of Codexis Inc share price expectations, FactSet research, analysts set an average price target of 11 in the next 12 months, up nearly 275.43% from the previous closing price of $2.93. Analysts anticipate Codexis Inc stock to reach 11 by 2025, with the lowest price target being 11. In spite of this, 3 analysts ranked Codexis Inc stock as Buy at the end of 2025.

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