Investors can expect a company’s stock to rise or fall based on the buying and selling of stock by its insiders. Exelixis Inc shares valued at $4,355,000 were sold by PAPADOPOULOS STELIOS on Nov 12 ’25. At $43.55 per share, PAPADOPOULOS STELIOS sold 100,000 shares. The insider’s holdings dropped to 1,189,228 shares worth approximately $50.11 million following the completion of this transaction.
Also, Aftab Dana sold 48,383 shares, netting a total of over 2,056,278 in proceeds. Following the sale of shares at $42.50 each, the insider now holds 664,778 shares.
Before that, Beckerle Mary C had sold 24,622 shares from its account. In a trade valued at $1,032,414, the Director traded Exelixis Inc shares for $41.93 each. Upon closing the transaction, the insider’s holdings decreased to 24,622 shares, worth approximately $0.9 million.
As published in their initiating research note from Wolfe Research on November 18, 2025, Exelixis Inc [EXEL] has been a Peer perform. Analysts at Guggenheim downgraded the stock from ‘”a Buy”‘ to ‘”a Neutral”‘ outlook in a report released in early November. As of October 21, 2025, Leerink Partners has increased its “Market perform” rating to a “an Outperform” for EXEL.
Analyzing EXEL Stock Performance
On last trading session, Exelixis Inc [NASDAQ: EXEL] plunged -1.20% to $42.14. The stock’s lowest price that day was $41.65, but it reached a high of $42.99 in the same session. During the last five days, there has been a drop of approximately -3.33%. Over the course of the year, Exelixis Inc shares have jumped approximately 22.32%. Shares of the company reached a 52-week high of $49.62 on 06/23/25 and a 52-week low of $31.90 on 01/24/25.
Support And Resistance Levels for Exelixis Inc (EXEL)
According to the 24-hour chart, there is a support level at 41.53, which, if violated, would cause prices to drop to 40.92. In the upper region, resistance lies at 42.87. The next price resistance is at 43.60. RSI (Relative Strength Index) is 58.04 on the 14-day chart, showing neutral technical sentiment.
Is Exelixis Inc subject to short interest?
Stocks of Exelixis Inc saw a sharp rise in short interest on 2025-10-31 jumping by 2.04 million shares to 19.79 million. Data from Yahoo Finance shows that the short interest on 2025-09-30 was 17.75 million shares. A jump of 10.33% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 7.11 of the overall float, the days-to-cover ratio (short ratio) jumped to 7.11.
Which companies own the most shares of Exelixis Inc (EXEL)?
In terms of Exelixis Inc share price expectations, FactSet research, analysts set an average price target of 44 in the next 12 months, up nearly 3.17% from the previous closing price of $42.65. Analysts anticipate Exelixis Inc stock to reach 56 by 2025, with the lowest price target being 30. In spite of this, 8 analysts ranked Exelixis Inc stock as Buy at the end of 2025. On September 17, 2025, Barclays assigned a price target of “an Equal weight” to the stock and resumed coverage with a $40.
