Ionis Pharmaceuticals Inc’s recently made public that its Director HERMAN JOAN E unloaded Company’s shares for reported $3.17 million on Nov 19 ’25. In the deal valued at $72.13 per share,44,000 shares were sold. As a result of this transaction, HERMAN JOAN E now holds 46,086 shares worth roughly $3.51 million.
Then, Joan E. Herman bought 44,000 shares, generating $3,256,000 in total proceeds.
Before that, Birchler Brian sold 8,000 shares. Ionis Pharmaceuticals Inc shares valued at $609,379 were divested by the EVP, Corp and Development Ops at a price of $76.17 per share. As a result of the transaction, Birchler Brian now holds 48,826 shares, worth roughly $3.72 million.
JP Morgan upgraded its Ionis Pharmaceuticals Inc [IONS] rating to an Overweight from a a Neutral in a research note published recently A number of analysts have revised their coverage, including Goldman’s analysts, who increased its forecast for the stock in late September from “a Sell” to “a Neutral”. BMO Capital Markets also remained covering IONS and has increased its forecast on September 03, 2025 with a “an Outperform” recommendation from previously “Market perform” rating. Morgan Stanley revised its rating on July 31, 2025. It rated IONS as “an Overweight” which previously was an “an Equal-weight”.
Price Performance Review of IONS
On Friday, Ionis Pharmaceuticals Inc [NASDAQ:IONS] saw its stock jump 4.06% to $76.09. Over the last five days, the stock has gained 6.35%. Ionis Pharmaceuticals Inc shares have risen nearly 125.45% since the year began. Nevertheless, the stocks have risen 117.65% over the past one year. While a 52-week high of $76.78 was reached on 11/06/25, a 52-week low of $23.95 was recorded on 04/09/25.
Levels Of Support And Resistance For IONS Stock
The 24-hour chart illustrates a support level at 73.96, which if violated will result in even more drops to 71.82. On the upside, there is a resistance level at 77.27. A further resistance level may holdings at 78.44.
How much short interest is there in Ionis Pharmaceuticals Inc?
A steep rise in short interest was recorded in Ionis Pharmaceuticals Inc stocks on 2025-10-31, growing by 0.38 million shares to a total of 12.66 million shares. Yahoo Finance data shows the prior-month short interest on 2025-09-30 was 12.28 million shares. There was a rise of 3.02%, which implies that there is a positive sentiment for the stock.
