In a filing, Ionis Pharmaceuticals Inc revealed its Director WENDER JOSEPH H unloaded Company’s shares for reported $2.26 million on Dec 01 ’25. In the deal valued at $80.82 per share,28,000 shares were sold. As a result of this transaction, WENDER JOSEPH H now holds 36,035 shares worth roughly $2.94 million.
Then, Joseph Wender bought 14,479 shares, generating $1,187,133 in total proceeds.
Before that, KLEIN JOSEPH III sold 12,000 shares. Ionis Pharmaceuticals Inc shares valued at $960,000 were divested by the Director at a price of $80.00 per share. As a result of the transaction, KLEIN JOSEPH III now holds 0 shares, worth roughly $0.0.
JP Morgan upgraded its Ionis Pharmaceuticals Inc [IONS] rating to an Overweight from a a Neutral in a research note published recently. A number of analysts have revised their coverage, including Goldman’s analysts, who increased its forecast for the stock in late September from “a Sell” to “a Neutral”. BMO Capital Markets also remained covering IONS and has increased its forecast on September 03, 2025 with a “an Outperform” recommendation from previously “Market perform” rating. Morgan Stanley revised its rating on July 31, 2025. It rated IONS as “an Overweight” which previously was an “an Equal-weight”.
Price Performance Review of IONS
On Friday, Ionis Pharmaceuticals Inc [NASDAQ:IONS] saw its stock fall -0.16% to $81.68. Over the last five days, the stock has lost -1.27%. Ionis Pharmaceuticals Inc shares have risen nearly 128.09% since the year began. Nevertheless, the stocks have risen 133.64% over the past one year. While a 52-week high of $83.61 was reached on 12/04/25, a 52-week low of $23.95 was recorded on 04/09/25.
Levels Of Support And Resistance For IONS Stock
The 24-hour chart illustrates a support level at 80.73, which if violated will result in even more drops to 79.79. On the upside, there is a resistance level at 82.53. A further resistance level may holdings at 83.39.
How much short interest is there in Ionis Pharmaceuticals Inc?
A steep rise in short interest was recorded in Ionis Pharmaceuticals Inc stocks on 2025-11-14, growing by 0.52 million shares to a total of 14.22 million shares. Yahoo Finance data shows the prior-month short interest on 2025-10-15 was 13.7 million shares. There was a rise of 3.69%, which implies that there is a positive sentiment for the stock.
