WVE’s short interest shows a sharp rise on 2025-11-28

Anna Perez

The buying and selling of stock by a company’s insider give investors a sense that the stock will rise or fall in the future. Wave Life Sciences Ltd shares valued at $630,000 were sold by Rawcliffe Adrian on Dec 08 ’25. At $15.00 per share, Rawcliffe Adrian sold 42,000 shares. The insider’s holdings dropped to 12,700 shares worth approximately $0.26 million following the completion of this transaction.

Also, Wagner Heidi L sold 14,000 shares, netting a total of over 189,000 in proceeds. Following the sale of shares at $13.50 each, the insider now holds 44,930 shares.

Before that, HENRY CHRISTIAN O had sold 93,445 shares from its account. In a trade valued at $1,369,324, the Director traded Wave Life Sciences Ltd shares for $14.65 each. Upon closing the transaction, the insider’s holdings decreased to 93,445 shares, worth approximately $0.26 million.

As published in a research note from RBC Capital Mkts on December 09, 2025, Wave Life Sciences Ltd [WVE] has been rated up from a Sector perform to an Outperform and the price target has been revised to $27. Analysts at Wells Fargo started covering the stock with ‘”an Overweight”‘ outlook in a report released in mid October. As of August 04, 2025, Canaccord Genuity has initiated its “Buy” rating for WVE. Earlier on July 28, 2025, Oppenheimer initiated its rating. Their recommendation was “an Outperform” for WVE stock.

Analyzing WVE Stock Performance

On last trading session, Wave Life Sciences Ltd [NASDAQ: WVE] plunged -5.07% to $20.23. The stock’s lowest price that day was $18.88, but it reached a high of $20.74 in the same session. During the last five days, there has been a surge of approximately 183.33%. Over the course of the year, Wave Life Sciences Ltd shares have jumped approximately 32.48%. Shares of the company reached a 52-week high of $21.73 on 12/09/25 and a 52-week low of $5.28 on 04/09/25.

Support And Resistance Levels for Wave Life Sciences Ltd (WVE)

According to the 24-hour chart, there is a support level at 19.12, which, if violated, would cause prices to drop to 18.01. In the upper region, resistance lies at 21.04. The next price resistance is at 21.85. RSI (Relative Strength Index) is 84.55 on the 14-day chart, showing overbought technical sentiment.

Is Wave Life Sciences Ltd subject to short interest?

Stocks of Wave Life Sciences Ltd saw a sharp rise in short interest on 2025-11-28 jumping by 2.66 million shares to 16.03 million. Data from Yahoo Finance shows that the short interest on 2025-10-31 was 13.37 million shares. A jump of 16.6% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 4.81 of the overall float, the days-to-cover ratio (short ratio) jumped to 4.81.

Which companies own the most shares of Wave Life Sciences Ltd (WVE)?

In terms of Wave Life Sciences Ltd share price expectations, FactSet research, analysts set an average price target of 28 in the next 12 months, up nearly 31.39% from the previous closing price of $21.31. Analysts anticipate Wave Life Sciences Ltd stock to reach 40 by 2025, with the lowest price target being 21. In spite of this, 3 analysts ranked Wave Life Sciences Ltd stock as Buy at the end of 2025. On July 16, 2025, Citigroup assigned a price target of “a Buy” to the stock and initiated coverage with a $16.

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