Investors can expect a company’s stock to rise or fall based on the buying and selling of stock by its insiders. Madrigal Pharmaceuticals Inc shares valued at $3,303,210 were purchased by William John Sibold on Sep 09 ’25. At $453.80 per share, William John Sibold acquired 7,279 shares.
Also, Sibold William John sold 7,279 shares, netting a total of over 3,243,741 in proceeds. Following the sale of shares at $445.63 each, the insider now holds 102,474 shares.
Before that, FRED CRAVES had added 2,900 shares to its account. In a trade valued at $1,251,896, the Former Director bought Madrigal Pharmaceuticals Inc shares for $431.69 each.
As published in their initiating research note from Truist on October 15, 2025, Madrigal Pharmaceuticals Inc [MDGL] has been a Buy and the price target has been revised to $580. As of February 28, 2025, B. Riley Securities has increased its “Neutral” rating to a “Buy” for MDGL. Earlier on February 27, 2025, H.C. Wainwright resumed its rating. Their recommendation was “a Buy” for MDGL stock.
Analyzing MDGL Stock Performance
On last trading session, Madrigal Pharmaceuticals Inc [NASDAQ: MDGL] plunged -1.77% to $421.6. The stock’s lowest price that day was $393.605, but it reached a high of $434.4817 in the same session. During the last five days, there has been a surge of approximately 1.36%. Over the course of the year, Madrigal Pharmaceuticals Inc shares have jumped approximately 100.12%. Shares of the company reached a 52-week high of $463.63 on 10/01/25 and a 52-week low of $265.00 on 05/27/25.
Support And Resistance Levels for Madrigal Pharmaceuticals Inc (MDGL)
According to the 24-hour chart, there is a support level at 398.64, which, if violated, would cause prices to drop to 375.69. In the upper region, resistance lies at 439.52. The next price resistance is at 457.44. RSI (Relative Strength Index) is 45.60 on the 14-day chart, showing neutral technical sentiment.
Is Madrigal Pharmaceuticals Inc subject to short interest?
Stocks of Madrigal Pharmaceuticals Inc saw a sharp steep in short interest on 2025-10-15 dropping by -0.45 million shares to 3.69 million. Data from Yahoo Finance shows that the short interest on 2025-09-15 was 4.14 million shares. A decline of -12.19% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 12.14 of the overall float, the days-to-cover ratio (short ratio) decline to 12.14.
Which companies own the most shares of Madrigal Pharmaceuticals Inc (MDGL)?
In terms of Madrigal Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 560 in the next 12 months, up nearly 30.48% from the previous closing price of $429.18. Analysts anticipate Madrigal Pharmaceuticals Inc stock to reach 590 by 2025, with the lowest price target being 420. In spite of this, 11 analysts ranked Madrigal Pharmaceuticals Inc stock as Buy at the end of 2025.
