Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Madrigal Pharmaceuticals Inc shares valued at $13,694,158 were sold by FRIEDMAN PAUL A on Dec 10 ’25. At $552.18 per share, FRIEDMAN PAUL A sold 24,800 shares. The insider’s holdings dropped to 187,164 shares worth approximately $112.83 million following the completion of this transaction.
Also, Taub Rebecca sold 18,650 shares, netting a total of over 10,297,573 in proceeds. Following the sale of shares at $552.15 each, the insider now holds 461,044 shares.
Before that, PAUL FRIEDMAN had added 49,600 shares to its account. In a trade valued at $27,474,432, the Director bought Madrigal Pharmaceuticals Inc shares for $553.92 each.
As published in a research note from Cantor Fitzgerald on November 05, 2025, Madrigal Pharmaceuticals Inc [MDGL] has been rated up from a Neutral to an Overweight. Analysts at BofA Securities upgraded the stock from ‘”an Underperform”‘ to ‘”a Neutral”‘ outlook in a report released in early November. As of October 15, 2025, Truist has initiated its “Buy” rating for MDGL.
Analyzing MDGL Stock Performance
On last trading session, Madrigal Pharmaceuticals Inc [NASDAQ: MDGL] rose 0.10% to $602.82. The stock’s lowest price that day was $601.36, but it reached a high of $614.36 in the same session. During the last five days, there has been a surge of approximately 10.37%. Over the course of the year, Madrigal Pharmaceuticals Inc shares have jumped approximately 95.44%. Shares of the company reached a 52-week high of $615.00 on 12/24/25 and a 52-week low of $265.00 on 05/27/25.
Support And Resistance Levels for Madrigal Pharmaceuticals Inc (MDGL)
According to the 24-hour chart, there is a support level at 597.79, which, if violated, would cause prices to drop to 592.75. In the upper region, resistance lies at 611.43. The next price resistance is at 620.03. RSI (Relative Strength Index) is 65.56 on the 14-day chart, showing neutral technical sentiment.
Is Madrigal Pharmaceuticals Inc subject to short interest?
Stocks of Madrigal Pharmaceuticals Inc saw a sharp steep in short interest on 2025-11-28 dropping by 13944.0 shares to 3.72 million. Data from Yahoo Finance shows that the short interest on 2025-10-31 was 3.74 million shares. A decline of -0.37% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 8.39 of the overall float, the days-to-cover ratio (short ratio) decline to 8.39.
Which companies own the most shares of Madrigal Pharmaceuticals Inc (MDGL)?
In terms of Madrigal Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 645 in the next 12 months, up nearly 7.11% from the previous closing price of $602.21. Analysts anticipate Madrigal Pharmaceuticals Inc stock to reach 900 by 2025, with the lowest price target being 527. In spite of this, 11 analysts ranked Madrigal Pharmaceuticals Inc stock as Buy at the end of 2025. On February 28, 2025, B. Riley Securities assigned a price target of “a Buy” to the stock and upgraded coverage with a $422.






