Investors can expect a company’s stock to rise or fall based on the buying and selling of stock by its insiders. Agios Pharmaceuticals Inc shares valued at $507,973 were purchased by Goff Brian on Dec 30 ’25. At $27.16 per share, Goff Brian acquired 18,703 shares.
Also, Gheuens Sarah purchased 2,932 shares, netting a total of over 79,633 in proceeds.
Before that, Jones Cecilia had added 2,932 shares to its account. In a trade valued at $79,633, the Officer bought Agios Pharmaceuticals Inc shares for $27.16 each.
As published in their initiating research note from Truist on November 24, 2025, Agios Pharmaceuticals Inc [AGIO] has been a Buy. Analysts at Leerink Partners upgraded the stock from ‘”a Market perform”‘ to ‘”an Outperform”‘ outlook in a report released in mid November. As of November 19, 2025, RBC Capital Mkts has decreased its “an Outperform” rating to a “Sector perform” for AGIO. Earlier on February 24, 2025, H.C. Wainwright initiated its rating. Their recommendation was “a Buy” for AGIO stock.
Analyzing AGIO Stock Performance
On last trading session, Agios Pharmaceuticals Inc [NASDAQ: AGIO] plunged -0.40% to $27.22. The stock’s lowest price that day was $26.74, but it reached a high of $27.61 in the same session. During the last five days, there has been a surge of approximately 10.70%. Over the course of the year, Agios Pharmaceuticals Inc shares have dropped approximately -18.50%. Shares of the company reached a 52-week high of $46.00 on 11/18/25 and a 52-week low of $22.24 on 11/19/25.
Support And Resistance Levels for Agios Pharmaceuticals Inc (AGIO)
According to the 24-hour chart, there is a support level at 26.77, which, if violated, would cause prices to drop to 26.32. In the upper region, resistance lies at 27.64. The next price resistance is at 28.06. RSI (Relative Strength Index) is 44.97 on the 14-day chart, showing neutral technical sentiment.
Is Agios Pharmaceuticals Inc subject to short interest?
Stocks of Agios Pharmaceuticals Inc saw a sharp rise in short interest on 2025-12-15 jumping by 1.79 million shares to 6.13 million. Data from Yahoo Finance shows that the short interest on 2025-11-14 was 4.33 million shares. A jump of 29.29% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 2.29 of the overall float, the days-to-cover ratio (short ratio) jumped to 2.29.
Which companies own the most shares of Agios Pharmaceuticals Inc (AGIO)?
In terms of Agios Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 39 in the next 12 months, up nearly 42.7% from the previous closing price of $27.33. Analysts anticipate Agios Pharmaceuticals Inc stock to reach 62 by 2026, with the lowest price target being 25. In spite of this, 5 analysts ranked Agios Pharmaceuticals Inc stock as Buy at the end of 2026.






