Sharp increase in MIST’s short interest leads to surge in days-to-cover ratio

Samantha Gray

Investors can expect a company’s stock to rise or fall based on the buying and selling of stock by its insiders. Milestone Pharmaceuticals Inc shares valued at $96,750 were sold by Oliveto Joseph on Jan 08 ’26. At $2.25 per share, Oliveto Joseph sold 43,000 shares. The insider’s holdings dropped to 303,721 shares worth approximately $0.62 million following the completion of this transaction.

Also, Oliveto Joseph sold 500 shares, netting a total of over 1,125 in proceeds. Following the sale of shares at $2.25 each, the insider now holds 346,721 shares.

Before that, JOSEPH OLIVETO had added 79,500 shares to its account. In a trade valued at $170,925, the Director bought Milestone Pharmaceuticals Inc shares for $2.15 each.

As published in a research note from TD Cowen on December 15, 2025, Milestone Pharmaceuticals Inc [MIST] has been rated up from a Hold to a Buy and the price target has been revised to $8. Analysts at Wells Fargo started covering the stock with ‘”an Overweight”‘ outlook in a report released in mid September. Earlier on August 22, 2024, Rodman & Renshaw initiated its rating. Their recommendation was “a Buy” for MIST stock.

Analyzing MIST Stock Performance

The stock’s lowest price that day was $2.02, but it reached a high of $2.13 in the same session. During the last five days, there has been a drop of approximately -7.31%. Over the course of the year, Milestone Pharmaceuticals Inc shares have jumped approximately 3.57%.

Support And Resistance Levels for Milestone Pharmaceuticals Inc (MIST)

RSI (Relative Strength Index) is 44.96 on the 14-day chart, showing neutral technical sentiment.

Is Milestone Pharmaceuticals Inc subject to short interest?

Stocks of Milestone Pharmaceuticals Inc saw a sharp rise in short interest on 2025-12-31 jumping by 0.86 million shares to 8.25 million. Data from Yahoo Finance shows that the short interest on 2025-11-28 was 7.39 million shares. A jump of 10.43% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 0.87 of the overall float, the days-to-cover ratio (short ratio) jumped to 0.87.

Which companies own the most shares of Milestone Pharmaceuticals Inc (MIST)?

In terms of Milestone Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 8 in the next 12 months, up nearly 294.09% from the previous closing price of $2.03. Analysts anticipate Milestone Pharmaceuticals Inc stock to reach 8 by 2026, with the lowest price target being 8. In spite of this, 3 analysts ranked Milestone Pharmaceuticals Inc stock as Buy at the end of 2026. On June 20, 2023, Jefferies assigned a price target of “a Hold” to the stock and downgraded coverage with a $4.

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