Jefferies downgrades Opko Health Inc (OPK) rating to a Hold

Anna Perez

In a filing, Opko Health Inc revealed its CEO & Chairman FROST PHILLIP MD ET AL acquired Company’s shares for reported $0.21 million on Oct 31 ’25. In the deal valued at $1.42 per share,150,000 shares were bought. As a result of this transaction, FROST PHILLIP MD ET AL now holds 214,386,448 shares worth roughly $300.14 million.

Then, FROST PHILLIP MD ET AL bought 675,000 shares, generating $891,000 in total proceeds. Upon buying the shares at $1.32, the CEO & Chairman now owns 214,676,448 shares.

Before that, FROST PHILLIP MD ET AL bought 125,000 shares. Opko Health Inc shares valued at $169,712 were divested by the CEO & Chairman at a price of $1.36 per share. As a result of the transaction, FROST PHILLIP MD ET AL now holds 214,001,448 shares, worth roughly $299.6 million.

Jefferies downgraded its Opko Health Inc [OPK] rating to a Hold from a a Buy in a research note published recently. A number of analysts have revised their coverage, including JP Morgan’s analysts, who began to cover the stock in late April with a ‘”a Neutral”‘ rating. Barrington Research also remained covering OPK and has increased its forecast on June 29, 2023 with a “an Outperform” recommendation from previously “Mkt perform” rating. H.C. Wainwright started covering the stock on December 15, 2022. It rated OPK as “a Buy”.

Price Performance Review of OPK

On Monday, Opko Health Inc [NASDAQ:OPK] saw its stock jump 2.94% to $1.4. Over the last five days, the stock has lost -3.45%. Opko Health Inc shares have fallen nearly -7.89% since the year began. Nevertheless, the stocks have fallen -4.76% over the past one year. While a 52-week high of $2.04 was reached on 03/05/25, a 52-week low of $1.11 was recorded on 08/01/25.

Levels Of Support And Resistance For OPK Stock

The 24-hour chart illustrates a support level at 1.3667, which if violated will result in even more drops to 1.3333. On the upside, there is a resistance level at 1.4267. A further resistance level may holdings at 1.4533.

How much short interest is there in Opko Health Inc?

A steep rise in short interest was recorded in Opko Health Inc stocks on 2025-10-15, growing by 0.48 million shares to a total of 33.37 million shares. Yahoo Finance data shows the prior-month short interest on 2025-09-15 was 32.89 million shares. There was a rise of 1.45%, which implies that there is a positive sentiment for the stock.

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