Agios Pharmaceuticals Inc [AGIO] Shares Jump Approximately 32.78% Over the Year

Roman Campbell

Investors can expect a company’s stock to rise or fall based on the buying and selling of stock by its insiders. Agios Pharmaceuticals Inc shares valued at $107,441 were purchased by SARAH GHEUENS on Nov 11 ’25. At $43.78 per share, SARAH GHEUENS acquired 2,454 shares.

Also, Gheuens Sarah sold 200 shares, netting a total of over 8,762 in proceeds. Following the sale of shares at $43.81 each, the insider now holds 61,727 shares.

Before that, SARAH GHEUENS had added 200 shares to its account. In a trade valued at $8,762, the Officer bought Agios Pharmaceuticals Inc shares for $43.81 each.

As published in their initiating research note from H.C. Wainwright on February 24, 2025, Agios Pharmaceuticals Inc [AGIO] has been a Buy and the price target has been revised to $58. Analysts at Scotiabank started covering the stock with ‘”a Sector outperform”‘ outlook in a report released in mid October. Earlier on September 27, 2024, Leerink Partners downgraded its rating. Their new recommendation was “a Market perform” for AGIO stock which previously was a “an Outperform”.

Analyzing AGIO Stock Performance

On last trading session, Agios Pharmaceuticals Inc [NASDAQ: AGIO] plunged -0.52% to $43.63. The stock’s lowest price that day was $43.2, but it reached a high of $44.55 in the same session. During the last five days, there has been a surge of approximately 7.70%. Over the course of the year, Agios Pharmaceuticals Inc shares have dropped approximately -26.13%. Shares of the company reached a 52-week high of $44.55 on 11/12/25 and a 52-week low of $23.42 on 04/09/25.

Support And Resistance Levels for Agios Pharmaceuticals Inc (AGIO)

According to the 24-hour chart, there is a support level at 43.04, which, if violated, would cause prices to drop to 42.44. In the upper region, resistance lies at 44.39. The next price resistance is at 45.14. RSI (Relative Strength Index) is 60.00 on the 14-day chart, showing neutral technical sentiment.

Is Agios Pharmaceuticals Inc subject to short interest?

Stocks of Agios Pharmaceuticals Inc saw a sharp steep in short interest on 2025-10-31 dropping by -0.58 million shares to 4.6 million. Data from Yahoo Finance shows that the short interest on 2025-09-30 was 5.18 million shares. A decline of -12.57% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 8.31 of the overall float, the days-to-cover ratio (short ratio) decline to 8.31.

Which companies own the most shares of Agios Pharmaceuticals Inc (AGIO)?

In terms of Agios Pharmaceuticals Inc share price expectations, FactSet research, analysts set an average price target of 56 in the next 12 months, up nearly 27.68% from the previous closing price of $43.86. Analysts anticipate Agios Pharmaceuticals Inc stock to reach 56 by 2025, with the lowest price target being 56. In spite of this, 5 analysts ranked Agios Pharmaceuticals Inc stock as Buy at the end of 2025.

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