Negative sentiment towards ONC reflected by a jump of 15.45% in short interest

Anna Perez

The buying and selling of stock by a company’s insider give investors a sense that the stock will rise or fall in the future. BeOne Medicines Ltd ADR shares valued at $3,560,161 were purchased by XIAOBIN WU on Nov 12 ’25. At $356.02 per share, XIAOBIN WU acquired 10,000 shares.

Also, Lee Chan Henry sold 10,671 shares, netting a total of over 3,739,108 in proceeds. Following the sale of shares at $350.40 each, the insider now holds 0 shares.

Before that, CHAN LEE had added 13,659 shares to its account. In a trade valued at $4,666,188, the Officer bought BeOne Medicines Ltd ADR shares for $341.62 each.

As published in their initiating research note from Barclays on September 18, 2025, BeOne Medicines Ltd ADR [ONC] has been an Overweight and the price target has been revised to $385. Analysts at RBC Capital Mkts started covering the stock with ‘”an Outperform”‘ outlook in a report released in early April. As of March 03, 2025, BofA Securities has increased its “Neutral” rating to a “Buy” for ONC.

Analyzing ONC Stock Performance

On last trading session, BeOne Medicines Ltd ADR [NASDAQ: ONC] rose 9.84% to $377.47. The stock’s lowest price that day was $347.5, but it reached a high of $379.329 in the same session. During the last five days, there has been a surge of approximately 17.45%. Over the course of the year, BeOne Medicines Ltd ADR shares have jumped approximately 83.71%. Shares of the company reached a 52-week high of $379.33 on 11/12/25 and a 52-week low of $172.67 on 01/08/25.

Support And Resistance Levels for BeOne Medicines Ltd ADR (ONC)

According to the 24-hour chart, there is a support level at 356.87, which, if violated, would cause prices to drop to 336.27. In the upper region, resistance lies at 388.70. The next price resistance is at 399.93. RSI (Relative Strength Index) is 72.82 on the 14-day chart, showing overbought technical sentiment.

Is BeOne Medicines Ltd ADR subject to short interest?

Stocks of BeOne Medicines Ltd ADR saw a sharp rise in short interest on 2025-10-31 jumping by 0.24 million shares to 1.57 million. Data from Yahoo Finance shows that the short interest on 2025-09-30 was 1.32 million shares. A jump of 15.45% in short interest reflects a negative sentiment towards the stock. Despite the fact that short shares comprise just 7.2 of the overall float, the days-to-cover ratio (short ratio) jumped to 7.2.

Which companies own the most shares of BeOne Medicines Ltd ADR (ONC)?

In terms of BeOne Medicines Ltd ADR share price expectations, FactSet research, analysts set an average price target of 384 in the next 12 months, up nearly 11.74% from the previous closing price of $343.65. Analysts anticipate BeOne Medicines Ltd ADR stock to reach 385 by 2025, with the lowest price target being 383. On September 18, 2024, JMP Securities assigned a price target of “a Mkt outperform” to the stock and initiated coverage with a $288.

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