Investors can speculate about the future of a stock by watching how its insiders buy and sell stocks. Annovis Bio Inc shares valued at $200,000 were purchased by Maccecchini Maria-Luisa on Oct 28 ’25. At $2.05 per share, Maccecchini Maria-Luisa acquired 97,561 shares. The insider’s holdings grew to 1,212,020 shares worth approximately $2.95 million following the completion of this transaction.
Also, Hoffman Michael B purchased 975,610 shares, netting a total of over 2,000,000 in proceeds. Following the buying of shares at $2.05 each, the insider now holds 2,455,539 shares.
As published in a research note from D. Boral Capital on February 10, 2025, Annovis Bio Inc [ANVS] has been rated down from a Buy to a Hold. Analysts at Maxim Group upgraded the stock from ‘”a Hold”‘ to ‘”a Buy”‘ outlook in a report released in late October. As of December 29, 2023, Canaccord Genuity has initiated its “Buy” rating for ANVS. Earlier on July 07, 2021, Maxim Group resumed its rating. Their recommendation was “a Buy” for ANVS stock.
Analyzing ANVS Stock Performance
On last trading session, Annovis Bio Inc [NYSE: ANVS] rose 15.17% to $2.43. The stock’s lowest price that day was $2.17, but it reached a high of $2.489 in the same session. During the last five days, there has been a surge of approximately 19.12%. Over the course of the year, Annovis Bio Inc shares have dropped approximately -70.22%. Shares of the company reached a 52-week high of $5.60 on 01/03/25 and a 52-week low of $1.11 on 04/09/25.
Support And Resistance Levels for Annovis Bio Inc (ANVS)
According to the 24-hour chart, there is a support level at 2.24, which, if violated, would cause prices to drop to 2.04. In the upper region, resistance lies at 2.56. The next price resistance is at 2.68. RSI (Relative Strength Index) is 63.51 on the 14-day chart, showing neutral technical sentiment.
Is Annovis Bio Inc subject to short interest?
Stocks of Annovis Bio Inc saw a sharp steep in short interest on 2025-10-31 dropping by -0.37 million shares to 1.03 million. Data from Yahoo Finance shows that the short interest on 2025-09-30 was 1.4 million shares. A decline of -35.36% in short interest reflects a positive sentiment towards the stock. Despite the fact that short shares comprise just 0.84 of the overall float, the days-to-cover ratio (short ratio) decline to 0.84.
Which companies own the most shares of Annovis Bio Inc (ANVS)?
In terms of Annovis Bio Inc share price expectations, FactSet research, analysts set an average price target of 26 in the next 12 months, up nearly 1132.23% from the previous closing price of $2.11. Analysts anticipate Annovis Bio Inc stock to reach 30 by 2025, with the lowest price target being 21. In spite of this, 2 analysts ranked Annovis Bio Inc stock as Buy at the end of 2025.






