Insider Sale Alert: Codexis Inc [CDXS] – Is it Time to sell?

Roman Campbell

Codexis Inc’s recently made public that its 10% Owner Opaleye Management Inc. unloaded Company’s shares for reported $0.38 million on Nov 12 ’25. In the deal valued at $1.96 per share,192,459 shares were sold. As a result of this transaction, Opaleye Management Inc. now holds 196,012 shares worth roughly $0.32 million.

Then, De Vre Raymond sold 1,413 shares, generating $2,459 in total proceeds. Upon selling the shares at $1.74, the Director now owns 87,416 shares.

Before that, Opaleye Management Inc. sold 548,211 shares. Codexis Inc shares valued at $986,451 were divested by the 10% Owner at a price of $1.80 per share. As a result of the transaction, Opaleye Management Inc. now holds 223,461 shares, worth roughly $0.37 million.

The Benchmark Company downgraded its Codexis Inc [CDXS] rating to a Hold from a a Buy in a research note published recently. Cantor Fitzgerald began covering CDXS with “an Overweight” recommendation on May 30, 2024. The Benchmark Company revised its rating on February 29, 2024. It rated CDXS as “a Buy” which previously was an “a Hold”.

Price Performance Review of CDXS

On Friday, Codexis Inc [NASDAQ:CDXS] saw its stock jump 0.92% to $1.64. Over the last five days, the stock has lost -2.66%. Codexis Inc shares have fallen nearly -59.08% since the year began. Nevertheless, the stocks have fallen -65.51% over the past one year. While a 52-week high of $6.08 was reached on 01/03/25, a 52-week low of $1.61 was recorded on 11/14/25.

Levels Of Support And Resistance For CDXS Stock

The 24-hour chart illustrates a support level at 1.5900, which if violated will result in even more drops to 1.5350. On the upside, there is a resistance level at 1.7000. A further resistance level may holdings at 1.7550.

How much short interest is there in Codexis Inc?

A steep rise in short interest was recorded in Codexis Inc stocks on 2025-10-31, dropping by -0.53 million shares to a total of 4.55 million shares. Yahoo Finance data shows the prior-month short interest on 2025-09-30 was 5.08 million shares. There was a decline of -11.64%, which implies that there is a negative sentiment for the stock.

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